The quaint town of Santee in Orangeburg County rests by the Santee River Valley in central South Carolina. It's known for golf opportunities, with numerous courses nearby, but there's a whole lot more to do in this resort town. Check out these suggestions while planning your vacation to Santee.

Top vacation rentals in Santee

Property building
3.6
Good(293 Reviews)
Comfort Inn & Suites Santee I-95
Hotel
 in Santee
3star
1 king bed
Pool · Kitchen or Kitchenette · Air conditioner

Looking to create some memories in Santee? Look no further than our Hotel, Comfort Inn & Suites Santee I-95. Enjoy top-rated amenities including Air conditioner, Internet / Wifi and Smoking allowed, and more.

$$$$
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Property building
4.2
Excellent(663 Reviews)
Best Western PLUS Santee Inn
Hotel
 in Santee
3star
1 queen bed
Pool · Pets allowed · Kitchen or Kitchenette

Looking to create some memories in Santee? Look no further than our Hotel, Best Western PLUS Santee Inn. Enjoy top-rated amenities including Air conditioner, Internet / Wifi and Pets allowed, and more.

$$$$
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Property building, On site, Time of day, Sunset
3.1
Average(377 Reviews)
Travelodge by Wyndham Santee
Hotel
 in Santee
2star
1 king bed
Pool · Pets allowed · Air conditioner

This Hotel for $60 in Santee, is perfect for your next (business stay, family stay, couples stay, getaway vacation, etc.)

$$$$
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Lobby or reception
4.7
Outstanding(306 Reviews)
Fairfield Inn & Suites Santee
Hotel
 in Santee
3star
1 king bed
Pool · Pets allowed · Air conditioner

Looking for the perfect place to call home during your trip to Santee? This Hotel offers a comfort and style with top-notch amenities, including Air conditioner, Fireplace and Internet / Wifi, and more.

$$$$
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Vacation rentals with parking in Santee

Photo of the whole room
3.4
Average(295 Reviews)
Red Roof Inn Santee
Motel
 in Santee
1 king bed
Pets allowed · Kitchen or Kitchenette · Air conditioner

This Motel in Santee, is the right price for your (business stay, family stays, couples stay, getaway vacation, etc.) today!

$$$$
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Property building, Lobby or reception, Seating area, fireplace
Quality Inn & Suites
Hotel
 in Santee
2star
2 queen beds
Pool · Pets allowed · Kitchen or Kitchenette

Discover the beauty of Santee with a stay at Quality Inn & Suites, a top rated Hotel with amenities such as Air conditioner, Internet / Wifi and Pets allowed, and more.

$$$$
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Property building, On site
3.3
Average(35 Reviews)
Econo Lodge
Nature lodge
 in Santee
Garden · Pets allowed · Kitchen or Kitchenette

This Nature lodge in Santee, is the right price for your (business stay, family stays, couples stay, getaway vacation, etc.) today!

$$$$
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Property building, Day, On site, Time of day
3.1
Average(179 Reviews)
Super 8 by Wyndham Santee
Hotel
 in Santee
2star
2 full beds
Pool · Pets allowed · Kitchen or Kitchenette

When traveling to Santee, if you are looking for (business stays, family stays, couples stay, getaway vacation, etc.) this is the perfect place at $64 per night.

$$$$
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Santee

Santee travel guide

Let us help you plan your perfect Santee vacation. Our travel guide highlights things to do, places to see, favorite vacation rental amenities in Santee, and more.

Frequently asked questions

What are the most popular vacation rental amenities in Santee?

  • Parking
  • Internet / Wifi
  • Air conditioner

About Santee

Aside from golf, Santee offers lots of outdoor recreation opportunities. Lake Marion and Lake Moultrie are connected by a canal, making the area ideal for fishing, boating and exploring swamps. Several other attractions are worth a visit.
  • Santee National Wildlife Refuge: Take a wilderness trek at the refuge where wildlife thrives. Ducks, geese, raptor birds and alligators live in the natural habitat. Visitors can hike trails, view educational exhibits and capture photos at observations areas.
  • Santee South Carolina State Park: Explore this expansive park that covers 2,496 acres. It's a hotspot for fishing and the location of several fishing tournaments.
  • Palmetto Trail: Hike South Carolina's biggest pedestrian and bike path, which will run from the mountains to the ocean once completed. Twelve miles of trail are available for hiking in Santee.

What are the must-visit tourist attractions in Santee, SC?

Santee, SC is a great place to visit and has many attractions that should not be missed. Tourists should check out the Santee State Park, the Santee National Wildlife Refuge, the Santee Cooper Country Club, and the Santee Canal. Here are a few of the must-visit attractions in Santee, SC:

  • Santee State Park
  • Santee National Wildlife Refuge
  • Santee Cooper Country Club
  • Santee Canal

How can I get around in Santee, SC?

You can get around Santee, SC in several ways:

  • By car
  • By bike
  • By foot

There are also public transportation options like buses, taxis, and rideshare services available.

Where can I find affordable accommodation in Santee, SC?

Santee, SC offers a variety of affordable accommodation options for travelers. Here are some of the best options:

  • The Comfort Inn Santee: This hotel offers comfortable rooms at a great price.
  • The Days Inn Santee: This hotel offers a convenient location and great amenities.
  • The Quality Inn Santee: This hotel is located close to many attractions and offers great value.
  • The Best Western Santee: This hotel offers a variety of amenities and a great location.

Whether you're looking for a budget-friendly hotel or a luxurious one, Santee, SC has something for everyone!

What is the culture like in Santee, SC?

Santee is a small town in South Carolina with a population of approximately 1,000 people. The culture in Santee is very family-oriented and the town is known for its strong sense of community and southern hospitality. Here are five points to consider when thinking about the culture in Santee:

  • Friendly and welcoming people
  • Southern hospitality
  • Small-town values
  • Outdoor activities and recreation
  • Strong sense of community

Is Santee, SC safe to travel to?

Santee, SC is generally a safe place to travel to. Here are a few things to keep in mind:

  • Be aware of your surroundings and take precautions at night.
  • Be aware of local laws and customs.
  • Be aware of any potential natural disasters.

What are the popular shopping destinations in Santee, SC?

Santee, SC offers a variety of popular shopping destinations:

  • Santee Outlet Mall
  • Santee Flea Market
  • Santee Antique Mall

These shopping destinations offer a variety of items from clothing to antiques, and more!

What are the best neighborhoods to visit in Santee, SC?

The best neighborhoods to visit in Santee, SC are:

  • Downtown Santee
  • Santee State Park
  • Santee National Wildlife Refuge

Downtown Santee features a variety of shops and restaurants, while Santee State Park and Santee National Wildlife Refuge offer plenty of outdoor activities for visitors to enjoy.

Where is Santee, SC?

Santee, SC is a small town located in Orangeburg County, South Carolina. It is situated on the banks of the Santee River, and is known for its popular fishing and boating spots. It is also home to a variety of outdoor activities, including camping, hiking, and swimming.

What are the most popular vacation rental amenities in Santee, SC?

The most popular vacation rental amenities in Santee, SC are:

  • High-speed internet access
  • Air conditioning
  • Full kitchen
  • Outdoor grill
  • Cable television

These amenities allow vacationers to stay connected, stay cool during the hot summer months, and enjoy home-cooked meals and entertainment.

What are the top things to do in Santee, SC?

Santee, SC is a small town with a lot of charm! Here are some of the top things to do in Santee:

  • Visit the Santee State Park for camping, fishing, and hiking.
  • Check out the Santee Cooper Country Club for a round of golf.
  • Explore the Santee National Wildlife Refuge for a peaceful nature experience.
  • Take a boat tour of Lake Marion for some great views.

What do I need to know before visiting Santee, SC?

Before visiting Santee, SC, there are a few things you should know.

  • Santee is located in Orangeburg County, SC.
  • The climate in Santee is typically warm and humid, with temperatures ranging from the mid-30s in the winter to the mid-90s in the summer.
  • Santee is home to several attractions, including Lake Marion, Santee State Park, and the Santee National Wildlife Refuge.

When visiting Santee, you will want to bring comfortable clothing to stay cool in the summer heat and warm clothing for the cooler winter months.

What is the price range for rentals in Santee?

Vacation rentals in Santee have a price range between $56-$472. The average price for rentals in Santee is $81 per night.

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