Close to sailing, cycling, and more, this smoke-free vacation home brings it all within reach. Key West Express is within an easy 8-minute walk and Ostego Bay Marine Science Center is also a quick 12-minute walk away, so leave your car at the property, which offers onsite parking.

Once you get back, you can enjoy your surroundings with the heated pool and BBQ grill. As for the great indoors, you can come inside and enjoy the free WiFi and cable/satellite TV.

No need to pay for a restaurant every night, when you've got an oven and a refrigerator on hand, as well as a coffee maker and a toaster. And because there's a washer/dryer, you can go a bit lighter on your packing.