Choose from 880 vacation rentals located in Pickens County, South Carolina. Top filters in Pickens County include Air conditioner, Kitchen or Kitchenette, and Internet / Wifi. Prices range from $56 to $7,500 per night. Our most popular vacation rental types near Pickens County are House and Hotel.

Top vacation rentals in Pickens County

Property grounds
9.9 / 10.0
Outstanding(238 Ratings)
Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers
Cabin
 in Pickens
4 guests · 2 bedrooms · 2 baths
Garden · Pets allowed · Kitchen or Kitchenette

Looking to create some memories in Pickens County? Look no further than our Cabin, Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers. Enjoy top-rated amenities including Air conditioner, Fireplace and Internet / Wifi, and more.

$$$$
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Miscellaneous
9.9 / 10.0
Outstanding(217 Ratings)
Hidden Gem - Privacy, Tranquility
Cabin
 in Cleveland
4 guests · 2 bedrooms · 1 bath
Ski in / Ski out · Kitchen or Kitchenette · Air conditioner

Indulge in a peaceful retreat at Hidden Gem - Privacy, Tranquility, our elegant Cabin in Pickens County. Enjoy amenities including Air conditioner, Fireplace and Internet / Wifi, and more.

$$$$
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On site, Pool view, Swimming pool, Swimming pool
6.6 / 10.0
Outstanding(398 Ratings)
Days Inn by Wyndham Easley West Of Greenville/Clemson Area
Hotel
 in Easley
2-star
1 king bed
Pool · Pets allowed · Kitchen or Kitchenette
Most favorited

This Hotel in Pickens County, is the right price for your (business stay, family stays, couples stay, getaway vacation, etc.) today!

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Photo of the whole room, On site
7.4 / 10.0
Outstanding(286 Ratings)
Best Western Plus Clemson Hotel & Conference Center
Hotel
 in Clemson
3-star
2 queen beds
Pool · Pets allowed · Kitchen or Kitchenette

Looking to create some memories in Pickens County? Look no further than our Hotel, Best Western Plus Clemson Hotel & Conference Center. Enjoy top-rated amenities including Air conditioner, Internet / Wifi and Laundry, and more.

$$$$
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Search by amenity

Vacation rentals with air conditioning in Pickens County

Terrace/patio
10.0 / 10.0
Outstanding(211 Ratings)
Private Romantic Mountain Getaway
Cabin
 in Pickens
4 guests · 2 bedrooms · 2 baths
Garden · Kitchen or Kitchenette · Air conditioner
Top rated

Looking to create some memories in Pickens County? Look no further than our Cabin, Private Romantic Mountain Getaway. Enjoy top-rated amenities including Air conditioner, Dishwasher and Internet / Wifi, and more.

$$$$
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Property grounds
9.9 / 10.0
Outstanding(209 Ratings)
Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
House
 in Seneca
15 guests · 6 bedrooms · 4 baths
Ski in / Ski out · Garden · Pets allowed

Are you ready to indulge in a relaxing getaway? Our House in Pickens County has everything you need for a rejuvenating stay. Treat yourself to Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks's exceptional amenities, such as Air conditioner, Dishwasher and Fireplace.

$$$$
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Property building
8.7 / 10.0
Outstanding(216 Ratings)
Holiday Inn Express Anderson I-85 - Exit 27- Highway 81, an IHG Hotel
Hotel
 in Anderson
2-star
2 full beds
Pool · Kitchen or Kitchenette · Air conditioner

Experience the best of Pickens County with this Hotel available for $135. This property is equipped with amenities including Air conditioner, Internet / Wifi and Laundry, and more.

$$$$
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Property building
8.6 / 10.0
Outstanding(63 Ratings)
Courtyard Clemson
Hotel
 in Clemson
3-star
1 king bed, 1 sofa bed
Pool · Kitchen or Kitchenette · Air conditioner
Most favorited

This inviting Hotel in Pickens County can fit your needs for many types of vacations, at $145 per night.

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Pickens County

Pickens County travel guide

Let us help you plan your perfect Pickens County vacation. Our travel guide highlights things to do, places to see, favorite vacation rental amenities in Pickens County, and more.

Frequently asked questions

What are the top travel destinations in Pickens County

Lake Keowee, Clemson, and Lake Jocassee are the top three destinations to travel in Pickens County.

What is the price range for rentals in Pickens County?

Vacation rentals in Pickens County have a price range between $56-$7,500. The average price for rentals in Pickens County is $218 per night.

How many cities have available rentals in Pickens County?

There are 5 destinations with available rentals in Pickens County.

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